Tracerlab: Scientific collaboration
We, as Tracerlab, are looking to collaborate with medical researchers, preferably educational institutions, who are looking for the synthetic development and initial in vitro validation of PET/optical/MRI tracers.


Collaborate with medical researchers, who are looking for the synthetic development and initial in vitro validation of PET/optical/MRI tracers.
What we're looking for
We, as Tracerlab, are looking to collaborate with medical researchers, preferably educational institutions, who are looking for the synthetic development and initial in vitro validation of PET/optical/MRI tracers. Typically, we're looking to collaborate with someone who is looking to visualize a process/receptor/enzyme/etc, knows from literature a good chemical entity that could be used (enzyme inhibitor, receptor ligand, etc.) but has no idea how to make it and then modify it towards an imaging modality. Sometimes, this person is uncertain what imaging modality to use and we can help.
We're not just looking to collaborate with medical researchers, but also with preclinical scientists looking for collaboration and students interested in BSc, MSc and PhD programs.
Ready to collaborate?Contact us today!
Expertise & Facilities
FFC Relaxometry: T1 NMRD profile acquisition using Stelar SMARtracer equipment

Expertise

PET-tracer assortment for human studies
Facilities

NMRD Relaxometer
Stelar 0.25 T FFC relaxometer SMARtracer.

Preparative HPLC
Shimadzu HPLC system.

Spectrofluorimeter
Edinburgh Instruments FS5 spectrofluorometer equipped with the SC-20 Thermostatic Sample Holder and integrating sphere (SC-30) for fluorescence quantum yield measurements.

Eckert&Ziegler synthesis module for research tracers

Quality control system for FDG

UV-Vis spectrophotometer with in situ irradiation setup
Agilent Cary 60 spectrophotometer with a custom-built (Prizmatix) multi-wavelength fiber coupled LED-system (FC10-LED-USB) connected through a fiber bundle attached to a liquid light guide.
Various synthesis modules for PET-tracer production
Synthra, Scintomics, Trasis, Eckert&Ziegler Pharmtracer, IBA Synthera
Meet the team
See who's involved with Tracerlab right now and who's been involved in the past.

Annemarie Doze, MSc
Current member

Guilherme Pietro da Silva, MSc
Current member

Luiza Reali Nazario, Dr
Current member

Melody Boëtius, MSc
Current member

Meryl Maria Vilangattil, MSc
Current member

Friederike Reessing, PhD
Past member

Ilse Welleman, PhD
Past member
Ready to collaborate?Contact us today!
Publications


J. Am. Chem. Soc. 2021, 143, 10041-10047
Ultrafast Photoclick Reaction for Selective 18F-Positron Emission Tomography Tracer Synthesis in Flow
Youxin Fu, Hugo Helbert, Nadja A. Simeth, Stefano Crespi, Gerbren B. Spoelstra, Jan Maarten van Dijl, Marleen van Oosten, Luiza Reali Nazario, Dion van der Born, Gert Luurtsema, Wiktor Szymanski,* Philip H. Elsinga,* Ben L. Feringa*
![Cross-coupling of [11C]methyllithium for 11C-labelled PET tracer synthesis](/images/publications/Hugo11C.gif)



ACS Omega 2020, 5, 22071-22080
A Facile and Reproducible Synthesis of Near-Infrared Fluorescent Conjugates with Small Targeting Molecules for Microbial Infection Imaging
Friederike Reeßing, Mafalda Bispo, Marina López-Álvarez, Marleen van Oosten, Ben L. Feringa, Jan Maarten van Dijl, Wiktor Szymanski*


Curr. Opin. Biotech. 2019, 58, 9-18
Following nanomedicine activation with magnetic resonance imaging: why, how, and what's next?
Friederike Reeßing, Wiktor Szymanski*





![Synthesis and in vitro evaluation of spirobenzovesamicols as potential 11C-PET tracer alternatives to [18F]FEOBV for vesicular acetylcholine transporter (VAChT) imaging](https://tracerlab.aloia.nl/uploads/41181_2025_327_Sch1_HTML_72333cd7dd.png)


![Synthesis and preclinical evaluation of [18F]AlF-NODA-MP-C6-CTHRSSVVC as a PET tracer for CD163-positive tumor-infiltrating macrophages](https://tracerlab.aloia.nl/uploads/1_s2_0_S0969805124000726_gr1_b5cdc90418.jpg)




![Phosphoramidite accelerated copper(i)-catalyzed [3 + 2] cycloadditions of azides and alkynes](/images/publications/LachlanCC.gif)